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Empagliflozin CAS: 864070-44-0 Onye na-ebuputa ihe.

Empagliflozin bụ ngwakọta C-glycosyl nke nwere ihe fọdụrụ na beta-glucosyl nwere otu (4-chloro-3-{4-[(3S))-tetrahydrofuran-3-yloxy] benzyl phenyl n'ime etiti anomeric, sodium-glucose. co-transporter 2 inhibitor na-eji dị ka ihe mgbakwunye nri na mmega ahụ iji melite njikwa glycemic na ndị okenye nwere ụdị ọrịa shuga mellitus nke 2. Ọ nwere ọrụ dị ka onye na-egbochi protein subtype 2 nke sodium-glucose na onye nnọchi anya hypoglycemic. Ngwakọta, ether aromatic, tetrahydrofuryl ether na onye otu monochlorobenzenes.


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Ngwa na Mmetụta

Empagliflozin bụ akwụkwọ akụkọ, nke nwere ike ma họrọ SGLT-2 inhibitor, na-eme ka njikwa glycemic na njirimara nke ọrịa metabolic na oke oke mamịrị. na-eme ka akịrị na-ewepụ shuga dị n'ọbara ma wepụ ya na mmamịrị.Empagliflozin nwere ike ịkpata akpịrị ịkpọ nkụ ma mee ka ọbara mgbali elu belata, na-ebute ndị ọrịa nwere isi ọwụwa ma ọ bụ nkụda mmụọ ma belata ọrụ akụrụ.Ihe ize ndụ nke ndị ọrịa meworo agadi, karịsịa ndị nwere ọrụ akụrụ na-adịghị mma na ndị diuretics, na-egosi na ọ ka ukwuu.FDA chọrọ Boehring na Eli Lilly ka ha na-eduzi ọmụmụ ihe anọ na-azụ ahịa: zuru ezu na-aga n'ihu na nyocha nke ọrịa obi, pharmacokinetics ụmụaka na pharmacodynamics, nchekwa ụmụaka na ịdị irè. ọnwụnwa, toxicity ule maka ọgwụ (karịsịa mmetụta maka renal ọrụ, ọkpụkpụ na ibu na mmepe).

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Ihe mejupụtara C23H27ClO7
Nyocha 99%
Ọdịdị Ọcha ntụ ntụ
CAS Mba. 864070-44-0
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Ndụ shelf afọ 2
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