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Pitavastatin CAS: 147511-69-1 Onye na-emepụta ihe

Pitavastatin bụ ihe na-egbochi HMG-CoA reductase nke na-eme ka usoro mbụ nke njikọ cholesterol dị elu.Ọ na-apụta dị ka enweghị isi ma na-acha ọcha na ntụ ntụ na-acha odo odo.Ọ na-ewe mmetụta site n'ibelata ọkwa nke ụfọdụ abụba abụba dị ka cholesterol n'ime ahụ.Ya mere, a na-egosi ya maka ọgwụgwọ hypercholesterolemia na maka mgbochi nke ọrịa obi.Ọ bụghị naanị na ọ nwere ike belata cholesterol dị elu na triglyceride na ụfọdụ ndị ọrịa, kamakwa ọ nwere ike ịbawanye ọdịnaya nke lipoproteins dị elu (HDL), ọkwa cholesterol “dị mma”.Ekwesịrị iji nri kwesịrị ekwesị na-enye ya n'ozuzu ya.


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Ngwa na Mmetụta

Pivastatin bụ ọgwụ mgbochi hyperlipidemic.Ọ bụghị naanị akwụkwọ akụkọ, nke na-arụ ọrụ nke ọma, nchekwa na kemịkalụ synthesized statin dabeere lipid-ebelata ọgwụ nwere ọnụ ahịa kachasị ọnụ ahịa, mana ọ bụkwa ihe mgbochi siri ike nke 3-hydroxy-3-methylglutaryl CoA (HMG-CoA reductase) reductase.Ọ bụghị nanị na ọ nwere mmetụta siri ike na mbenata LDL-C na TC, kamakwa ọ nwere nnukwu mkpụrụ ndụ polymorphism, nnukwu bioavailability, na ogologo ndụ ọkara ndụ Na naanị ole na ole na-enweta CYP2C9 metabolism. Ejiri ya na-agwọ hyperlipidemia mbụ, hypercholesterolemia ezinụlọ, na ngwakọta lipid. nsogbu.

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CAS Mba. 147511-69-1
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