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β-Nicotinamide Mononucleotide CAS: 1094-61-7

Nicotinamide mononucleotide (NMN), ngwaahịa nke mmeghachi omume NAMPT na isi NAD + etiti, na-eme ka nnabata glucose dị elu site na iweghachi ọkwa NAD + na ụmụ oke T2D kpatara HFD.NMN na-akwalitekwa mmetụta insulin imeju ma weghachi okwu mkpụrụ ndụ ihe nketa metụtara nrụgide oxidative, nzaghachi mkpali, na rhythm circadian, akụkụ site na ịgbalite SIRT1.A na-eji NMN maka ọmụmụ ihe ejikọtara n'ime RNA aptamers na usoro ịgbalite ribozyme gụnyere β-nicotinamide mononucleotide (β-NMN) -arụ ọrụ RNA iberibe.


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Ngwa na Mmetụta

A na-eji β-Nicotinamide mononucleotide (NMN) na-amụ ihe ejikọtara n'ime RNA aptamers na usoro ntinye ribozyme gụnyere β-nicotinamide mononucleotide (β-NMN) -arụ ọrụ RNA iberibe.NMN bụ nucleotide sitere na ribose na nicotinamide.Niacinamide (nicotinamide,) bụ ihe sitere na vitamin B3, nke a makwaara dị ka niacin.) Dị ka biochemical precursor nke NAD +, ọ nwere ike ịba uru na mgbochi nke pellagra.
β-Nicotinamide mononucleotide bụ etiti na biosynthesis nke nicotinamide adenine dinucleotide (NAD+).Nicotinamide phosphoribosyltransferase (Nampt) na-eme ka condensation nke nicotinamide na 5-phosphoribosyl-1-pyrophosphate na-emepụta β-NMN, bụ nke emesị gbanwee gaa na NAD + site na β-NMN adenyltransferase.At 50-100 β-M ka ejirila μM. NAD biosynthesis na insulin na-akpali akpali n'ụdị Nampt +/- òké nke ọrịa metabolic, na-egosipụta ọrụ maka Nampt na ọrụ β cell.

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Ihe mejupụtara C11H15N2O8P
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CAS Mba. 1094-61-7
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