β-Nicotinamide Mononucleotide CAS:1094-61-7

Nicotinamide mononucleotide (NMN), ihe sitere na mmeghachi omume NAMPT na isi ihe dị mkpa nke NAD+ etiti, na-ebelata enweghị ike glucose site na iweghachi ọkwa NAD+ na òké T2D nke HFD kpatara. NMN na-emekwa ka mmetụta insulin imeju dịkwuo mma ma weghachite ngosipụta mkpụrụ ndụ ihe nketa metụtara nrụgide oxidative, nzaghachi mkpali, na ụda circadian, nke ụfọdụ site na mmalite SIRT1. A na-eji NMN eme ihe maka ịmụ ihe ndị na-ejikọ ọnụ n'ime RNA aptamers na usoro mkpali ribozyme nke gụnyere iberibe RNA β-nicotinamide mononucleotide (β-NMN) nke na-arụ ọrụ.

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Nkọwa Ngwaahịa

Akara Ngwaahịa

Ngwa na Mmetụta

A na-eji β-Nicotinamide mononucleotide (NMN) amụ ihe gbasara njikọ n'ime aptamers RNA na usoro mkpali ribozyme nke gụnyere iberibe RNA nke β-nicotinamide mononucleotide (β-NMN). NMN bụ nucleotide sitere na ribose na nicotinamide. Niacinamide (nicotinamide,) bụ ihe sitere na vitamin B3, nke a makwaara dị ka niacin.) Dịka ihe na-ebute NAD+ na biochemical, ọ nwere ike ịba uru na mgbochi nke pellagra.
β-Nicotinamide mononucleotide bụ ihe dị n'etiti na biosynthesis nke nicotinamide adenine dinucleotide (NAD+). Nicotinamide phosphoribosyltransferase (Nampt) na-akwalite njikọta nke nicotinamide na 5-phosphoribosyl-1-pyrophosphate iji mepụta β-NMN, nke β-NMN adenyltransferase na-agbanwe ka ọ bụrụ NAD+. Na 50-100 μM, ejirila β-NMN mee ka biosynthesis NAD na mmepụta insulin nke glucose na-akpali na ụdị Nampt+/- òké nke ọrịa metabolic, na-egosi ọrụ maka Nampt na ọrụ β cell.

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Ihe mejupụtara ya	C11H15N2O8P
Nnwale	99%
Ọdịdị	Ntụ ntụ ọcha
Nọmba CAS	1094-61-7
Nkwakọ ngwaahịa	25KG
Ndụ nchekwa	afọ 2
Nchekwa	Debe n'ebe dị jụụ ma kpọọ nkụ
Asambodo	ISO.