(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride CAS:188416-35-5

A na-eji (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride eme ihe na kemistri ọgwụ maka ọrụ ọgwụ ya na ojiji ọgwụgwọ ya. Ngwakọta a nwere ike igosipụta ihe mgbochi mgbasa, mgbochi mbufụt, ma ọ bụ ihe mgbochi enzyme bara uru na ọgwụgwọ nke ọrịa dị iche iche, gụnyere kansa, mbufụt, na ọnọdụ ọrịa. Na nchọpụta ọgwụ, ndị nchọpụta na-eji (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride emepụta ma mepụta ngwakọta ọhụrụ nwere ike, nhọrọ, na nnweta bioavailability. Site na ịgbanwe nhazi kemịkalụ ya na inyocha mmekọrịta nhazi na ọrụ, ndị ọkà mmụta sayensị na-achọ ịmepụta ndị na-agwọ ọrịa ọhụrụ na-elekwasị anya na ụzọ molekul na ebumnuche bayoloji nke metụtara ọrịa. Ọzọkwa, ngwakọta a na-eje ozi dị ka ihe ndabere molekul maka njikọta nke ndị nwere ike inweta ọgwụ nwere profaịlụ pharmacokinetic kachasị mma na arụmọrụ ọgwụgwọ ka mma. Mmekọrịta ya na ebumnuche sel, ụzọ mgbaàmà, na ihe ngosi ọrịa na-enye nghọta banyere mmetụta ya na usoro ihe omume ya, na-eduzi mmepe nke ọgwụgwọ ezubere iche na ọgwụgwọ ahaziri ahazi maka ndị ọrịa nwere mkpa ahụike na-emezughị. Ọzọkwa, enwere ike iji (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride na ọmụmụ ihe tupu a mụọ nchekwa, arụmọrụ, na akụrụngwa ọgwụ tupu ọ gaa n'ihu na nnwale ahụike. A na-enyocha ọrụ bioactivity ya, mmetụta pharmacodynamic ya, na mmetụta ndị nwere ike ịkpata iji chọpụta ikike ọgwụgwọ ya na dabara adaba maka mmepe ọzọ dị ka ngwaahịa ọgwụ. N'ozuzu, (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride na-anọchite anya ihe bara uru na nyocha kemịkalụ ọgwụ, na-enye ohere maka nchọpụta ọgwụ, njikarịcha ndu, na ihe ọhụrụ ọgwụgwọ na ọchịchọ iji dozie ọnọdụ ahụike dị mgbagwoju anya na imeziwanye nsonaazụ ndị ọrịa.