(6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid CAS:30246-33-4

(6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, nke a makwaara dị ka [tinye aha azụmaahịa ma ọ bụ aha nkịtị ma ọ bụrụ na ọ dị mkpa], nwere nnukwu mkpa na nyocha ọgwụ na mmepe ọgwụ n'ihi ihe ndị dị na ọgwụ nje ya. Ngwakọta a na-arụ ọrụ dị ka ihe owuwu dị mkpa maka njikọta nke ihe ndị na-egbu nje bacteria e mere iji lekwasị anya na nje bacteria ụfọdụ ma gbochie uto ha. Nhazi nhazi ya na-enye ohere maka mmekọrịta ziri ezi na enzymes nje bacteria, na-emebi usoro dị mkpa ma na-eduga na mmetụta nje bacteria. Ọzọkwa, (6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid na-arụ ọrụ dị mkpa n'ịlụso ọrịa nje bacteria ọgụ nke na-eyi ahụike mmadụ egwu. Site n'itinye ihe a n'ime ọgwụ nje, ndị nchọpụta na-achọ ịmepụta nhọrọ ọgwụgwọ ọhụrụ nwere arụmọrụ ka mma na mbelata iguzogide. Usoro ihe omume nke ihe mejupụtara ya na-elekwasị anya na mgbidi mkpụrụ ndụ nje bacteria ma ọ bụ njikọ protein, na-enye ọtụtụ ọrụ megide ma nje bacteria Gram-positive na Gram-negative, gụnyere ụdị nje ndị na-eguzogide ọgwụ dị iche iche. Ọzọkwa, mgbalị nyocha na-elekwasị anya n'ịkwalite njirimara ọgwụ nke (6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid iji melite nnweta na nkesa ya n'ime ahụ. Usoro nhazi a gụnyere inyocha usoro nnyefe ọgwụ dị iche iche, dị ka prodrugs, nanoparticles, ma ọ bụ usoro liposomal, iji melite ikike ọgwụgwọ nke ogige ahụ ma belata mmetụta ndị ọzọ. Na mmechi, (6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid na-anọchite anya ihe bara uru n'akụkụ ọgwụgwọ ọrịa na-efe efe, na-enye ngwọta ndị na-ekwe nkwa maka ịgwọ iguzogide nje bacteria na imeziwanye nsonaazụ ndị ọrịa. Ojiji ya dị iche iche n'ọgwụgwọ ọgwụ nje na-eme ka ọ pụta ìhè na ọ dị mkpa n'ọgwụ ọgbara ọhụrụ ma na-egosipụta ike ya ịkwalite ihe ọhụrụ n'imepụta ọgwụ nje ndị na-abịa n'ihu.