Acetylthiocholine iodide CAS:1866-15-5

A na-ejikarị Acetylthiocholine iodide eme ihe dị ka ihe e ji amịpụta ihe iji tụọ ọrụ nke enzyme acetylcholinesterase (AChE). AChE bụ ọrụ maka imebi acetylcholine neurotransmitter na sistemụ akwara. Mgbakwunye nke acetylthiocholine iodide na ngwakọta mmeghachi omume nke nwere AChE na-eduga na mmepụta nke thiocholine na acetate.

Enwere ike ịchọpụta mmeghachi omume ahụ site na itinye ihe ngosi agba ma ọ bụ fluorometric nke na-emeghachi omume kpọmkwem na thiocholine. Ọnụego mmepụta agba ma ọ bụ fluorescence kwekọrọ kpọmkwem na ọrụ nke AChE na sample. Nke a na-eme ka acetylthiocholine iodide bụrụ ngwaọrụ bara uru maka ịtụ ọrụ AChE na ọtụtụ ihe nlele bayoloji, gụnyere anụ ahụ, ọdịbendị sel, na ọbara.

A na-eji acetylthiocholine iodide atụ ọrụ AChE nke ukwuu n'ọmụmụ ihe gbasara sistemu cholinergic, nsogbu akwara ozi, na ikpughe na kemịkalụ ma ọ bụ ọgwụ ụfọdụ nwere ike imetụta ọrụ AChE. A pụkwara iji ya dị ka ngwa nyocha maka ịchọpụta ihe mgbochi AChE, nke nwere mmasị na mmepe ọgwụ maka ọrịa dịka Alzheimer na Parkinson.

Tinyere iji ya eme ihe na nnwale enzymatic, enwere ike iji acetylthiocholine iodide dị ka ihe ndabere maka biosensors dabere na AChE. Emebere biosensors ndị a iji chọpụta ma tụọ ọnụnọ nke ụfọdụ ihe nwere ike igbochi ọrụ AChE, dị ka pesticides organophosphate ma ọ bụ ihe ndị na-akpata akwara.