Amphotericin B - Ọkwa ntụtụ CAS:1397-89-3

A na-eji ọgwụ Amphotericin B agwọ ọrịa fungal dị oke njọ dịka candidemia, aspergillosis invasive, meningitis cryptococcal, na mucormycosis, ọkachasị na ndị ọrịa nwere nsogbu ahụ ike ma ọ bụ ndị nwere sistemu ahụ ji alụso ọrịa ọgụ na-adịghị ike. N'ihi ọrụ antifungal dị ike ya, a na-ewerekarị ọgwụ amphotericin B dị ka ọgwụgwọ mbụ maka ọrịa fungal dị oke njọ. Ndị ọkachamara ahụike na-enye amphotericin B n'ime akwara, na-enyocha ndị ọrịa nke ọma n'oge ọgwụ iji jikwaa mmetụta ọjọọ nwere ike inwe, gụnyere ahụ ọkụ, oyi, na mmeghachi omume metụtara infusion. A na-ahazi usoro na oge ọgwụgwọ amphotericin B dabere na ọrịa fungal kpọmkwem, ọnọdụ ahụike onye ọrịa, na nsogbu ọ bụla dị n'ime akụkụ ahụ. N'ihi nephrotoxicity ya na ike ya maka nsogbu electrolyte, nlekota nke ọma nke ọrụ akụrụ na ọkwa electrolyte dị oke mkpa n'oge ọgwụgwọ amphotericin B. Enwere ike iji usoro lipid nke amphotericin B belata nsí akụrụ na mmeghachi omume metụtara infusion metụtara amphotericin B deoxycholate nkịtị. Nleba anya mgbe niile maka mmetụta ọjọọ, dị ka nsogbu akụrụ na hypokalemia, yana nlekọta nkwado kwesịrị ekwesị, na-enyere aka ijikwa nchekwa na nnabata nke ọgwụgwọ amphotericin B. Ndị na-ahụ maka ahụike na-atụle uru ọgwụgwọ ahụ nke ọma megide ihe egwu ndị nwere ike ibute, na-ahụ na ndị ọrịa na-enweta ọgwụgwọ antifungal kwesịrị ekwesị ebe ha na-ebelata mmetụta ọjọọ nke mmetụta ọjọọ. Site n'inyocha ọrịa fungal dị njọ nke sistemụ, ọgwụ amphotericin B na-arụ ọrụ dị mkpa n'ịgwọ ọnọdụ ndị na-eyi ndụ egwu ma na-enye nhọrọ ọgwụgwọ maka ndị ọrịa na-eche ọrịa fungal siri ike ihu.