beta-Nicotinamide adenine dinucleotide trihydrate CAS:53-84-9

Mmepụta ike: β-NAD+ bụ ihe dị mkpa n'usoro ịtụgharị nri ka ọ bụrụ ike. Ọ na-eje ozi dị ka coenzyme na iku ume sel, na-eme ka nnyefe elektrọn site na metabolites gaa na usoro mbufe elektrọn dị mfe. Mbufe elektrọn a dị mkpa maka mmepụta ATP, nke bụ isi ego ike nke mkpụrụ ndụ.

Ndozi DNA: β-NAD+ na-etinye aka na usoro ndozi DNA. Ọ na-arụ ọrụ dị ka ihe ndabere maka enzymes dịka PARPs (Poly [ADP-ribose] polymerases), nke na-eji β-NAD+ arụzi DNA mebiri emebi na nzaghachi maka nrụgide sel dị iche iche dịka mmebi DNA nke radieshon, nsí, ma ọ bụ nrụgide oxidative kpatara.

Mgbaàmà mkpụrụ ndụ: β-NAD+ apụtala dị ka molekul mgbaama dị mkpa nke metụtara ọtụtụ ụzọ mkpụrụ ndụ. Ọ nwere ike ịrụ ọrụ dị ka ihe na-ebute ụzọ maka molekul mgbaama dị iche iche, dị ka ADP-ribose cyclic na NAADP, nke na-achịkwa ntọhapụ calcium na transduction. Na mgbakwunye, metabolism β-NAD+ nwere ike imetụta ngosipụta mkpụrụ ndụ ihe nketa, ịka nká, na usoro physiological ndị ọzọ.

Ngwa ọgwụgwọ: A na-enyocha mgbakwunye β-NAD+ na mgbanwe nke ọkwa β-NAD+ maka ojiji ọgwụgwọ nwere ike. Nnyocha ndị e mere n'oge na-adịbeghị anya na-egosi na mmụba nke ọkwa β-NAD+ nwere ike inwe mmetụta bara uru na ọrịa ndị metụtara ịka nká, nsogbu neurodegenerative, nsogbu metabolic, na ahụike obi. Enwerekwa nnyocha na-aga n'ihu na ojiji nke β-NAD+ precursors, dị ka nicotinamide riboside na nicotinamide mononucleotide, dị ka ihe mgbakwunye nwere ike ime iji mee ka ọkwa β-NAD+ dịkwuo elu n'ahụ.