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Adenosine CAS:58-61-7
Adenosine bụ nucleoside nke mejupụtara adenine na ribose, na-arụ ọrụ dị mkpa na metabolism cellular. Ọ na-eje ozi dị ka ihe owuwu dị mkpa maka adenosine triphosphate (ATP), isi ihe na-akpata ike na sistemụ bayoloji. Karịa ọrụ ya metụtara ike, adenosine na-etinye aka na usoro dị iche iche nke physiological, gụnyere neurotransmission, vasodilation, na nhazi nke usoro ụra-teke. Ọ na-arụ ọrụ na ndị nnata kpọmkwem, na-emetụta ọnụego obi na ọbara. N'ọgwụgwọ, a na-eji adenosine eme ihe na ọgwụ, karịsịa n'ọgwụgwọ ụfọdụ arrhythmias obi. Ọrụ ya dị iche iche na-emesi ike mkpa nke adenosine na ahụike na ọrịa.
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Uridine 5-monophosphate, nnu disodium CAS:3387-36-8
Uridine 5-monophosphate, nnu disodium (UMP) bụ nucleotide nke na-arụ ọrụ dị mkpa na metabolism nke sel na njikọ RNA. Site na uracil pyrimidine base, shuga ribose, na otu phosphate, UMP dị oke mkpa maka usoro dị iche iche nke bayoloji, gụnyere ịmepụta nucleic acid na nhazi nke ụzọ metabolic. Ụdị nnu disodium na-eme ka ọ dịkwuo mma ịgbaze na nkwụsi ike na mmiri mmiri, na-eme ka ọ dabara adaba maka nyocha ụlọ nyocha na ngwa ọgwụgwọ. UMP enwetawo nlebara anya maka ihe ndị nwere ike ime ka neuroprotective na cognition dịkwuo mma, yana ọrụ ya n'ịkwalite ahụike sel dum.
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Cytidine 5′-(disodium phosphate) CAS:6757-06-8
Cytidine 5′-(disodium phosphate) bụ ihe sitere na nucleotide nke mejupụtara pyrimidine base cytosine, ribose sugar, na otu phosphate. Ihe mejupụtara a na-arụ ọrụ dị mkpa na usoro biochemical dị iche iche, gụnyere njikọ RNA, ụzọ nchịkwa, na akara mkpụrụ ndụ. Ụdị nnu disodium na-eme ka ọ dịkwuo mma ma kwụsie ike na ọnọdụ ahụike, na-eme ka ọ dabara adaba maka nyocha ụlọ nyocha na ojiji ọgwụgwọ nwere ike. Cytidine 5′-(disodium phosphate) enwetawo mmasị maka itinye aka ya na metabolism nucleic acid na uru ya nwere ike ịba ụba na ịkwalite ọrụ nghọta na ịkwado ahụike mkpụrụ ndụ.
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5-Azacytidine CAS:320-67-2
5-Azacytidine bụ ihe atụ nke nucleoside nke cytidine nke nwere atọm nitrogen n'ọnọdụ ise nke mgbanaka pyrimidine, na-anọchi atọm carbon. Mgbanwe a na-enye ihe pụrụ iche nke ọgwụ, na-eme ka ọ bụrụ ihe dị mkpa na bayoloji molekul na ọgwụgwọ kansa. Dịka onye na-egbochi DNA methyltransferase siri ike, 5-azacytidine nwere ike imegharị mkpụrụ ndụ ihe nketa ndị mechiri emechi site na ịgbanwe ụkpụrụ methylation DNA, si otú a na-emetụta ngosipụta mkpụrụ ndụ ihe nketa. E mepụtara 5-azacytidine na mbụ maka ịgwọ ọrịa kansa ọbara, 5-azacytidine enwetawo nlebara anya maka ojiji ya nwere ike na ọgwụgwọ epigenetic, ọgwụ regenerative, na nyocha na-elekwasị anya na ọrịa dị iche iche nke iwu mkpụrụ ndụ ihe nketa na-adịghị mma mara.
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2′-Fluoro-2′-deoxyuridine CAS:784-71-4
2′-Fluoro-2′-deoxyuridine (FdU) bụ ihe atụ nke nucleoside nke deoxyuridine, ebe atọm fluorine nọchiri atọm hydrogen dị n'ọnọdụ 2′ nke shuga ribose. Mgbanwe a na-eme ka nkwụsi ike na ọrụ bioactivity nke ihe mejupụtara ahụ dịkwuo mma, na-eme ka ọ baa uru na nyocha biochemical na ojiji ọgwụgwọ. A maara FdU karịsịa maka ọrụ ya dị ka ihe na-egbochi nje na ọrịa kansa, n'ihi na ọ nwere ike igbochi mmepụta DNA ma gbochie mmegharị nke ụfọdụ nje virus na mkpụrụ ndụ kansa. Ihe pụrụ iche ya na-eme ka ọ bụrụ ngwaọrụ dị mkpa na mmepe nke ọgwụgwọ ezubere iche na ọmụmụ ihe gbasara bayoloji molekul.
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![4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one CAS:10212-20-1](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT260.png)
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one CAS:10212-20-1
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one bụ ihe analog nucleoside dị mgbagwoju anya nke nwere ntọala pyrimidine nke ejikọtara na shuga ribose agbanwere agbanwe. Ọnụnọ nke atọm fluorine na otu hydroxyl n'ime nhazi ya na-eme ka njirimara biochemical ya dịkwuo mma, na-eme ka ọ bụrụ ihe na-adọrọ mmasị maka nyocha nje na mgbochi kansa. Ngwakọta a nwere ike itinye na kemistri ọgwụ, karịsịa dị ka ihe na-agwọ ọrịa na-elekwasị anya na njikọ nucleic acid na ụzọ metabolic na ihe ndị dị ndụ na-akpata ọrịa. Njirimara nhazi ya pụrụ iche na-enye ohere maka mmekọrịta ka mma na ihe mgbaru ọsọ bayoloji metụtara na DNA na RNA metabolism.
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1,3,5-tri-O-benzoyl-alpha-D-ribofuranose CAS:22224-41-5
1,3,5-Tri-O-benzoyl-alpha-D-ribofuranose bụ ụdị ribose nke e ji kemịkal gbanwee, nke nwere otu benzoyloxy atọ jikọtara na ọnọdụ 1, 3, na 5 nke nhazi ribofuranose. Mgbanwe a na-eme ka ọ dịkwuo mma ịgbaze na nkwụsi ike, na-eme ka ọ baa uru n'ọtụtụ ojiji sịntetik na kemistri organic na biochemistry. Dịka ihe e ji echekwa ribose, ọ na-eje ozi dị ka ihe etiti na njikọta nke nucleosides na nucleotides, ihe dị mkpa nke RNA na DNA. Njirimara pụrụ iche ya na-eme ka 1,3,5-tri-O-benzoyl-alpha-D-ribofuranose baa uru maka ndị nchọpụta na-achọ ịmepụta ihe ọgwụgwọ ọhụrụ na ihe ndị dị na kemistri nucleotide.
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2′-O-methyluridine CAS:2140-76-3
2′-O-Methyluridine bụ nucleoside nke na-eme n'okike ebe otu methyl na-ejikọta na atọm oxygen nke ọnọdụ 2′ nke shuga ribose na uridine. Mgbanwe a na-eme ka nkwụsi ike na ọrụ nke molekul RNA dịkwuo mma, na-eme ka ọ bụrụ ihe dị mkpa na usoro dị iche iche nke bayoloji. 2′-O-Methyluridine na-arụ ọrụ dị mkpa na nhazi na ọrụ nke ribonucleic acids (RNAs), gụnyere ozi RNA (mRNA) na mbufe RNA (tRNA). Ọnụnọ ya nwere ike imetụta nkwụsi ike RNA, arụmọrụ ntụgharị, na mmekọrịta ya na protein na acid nucleic ndị ọzọ, na-eme ka ọ bụrụ ihe dị mkpa na ọmụmụ nke bayoloji molekul na ngwa ọgwụgwọ.
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adenosine 5′-monophosphate sodium* sitere na yist CAS:4578-31-8
Adenosine 5′-monophosphate sodium (AMP) bụ nucleotide sitere na adenosine nke na-arụ ọrụ dị mkpa na metabolism sel. AMP dị mkpa maka usoro dị iche iche nke bayoloji, gụnyere nnyefe ike, transduction mgbaàmà, na dịka ihe na-ebute ụzọ maka mmepụta nke ATP na nucleotides ndị ọzọ. Enwere ike inweta ụdị nnu sodium nke AMP site na yist, nke bara ụba na nucleotides n'ihi ụzọ metabolic ya na-arụ ọrụ. A na-ejikarị ihe mejupụtara a na biochemistry na pharmacology dị ka ihe na-eme ka ihe dị ndụ dị ndụ, ihe mgbakwunye nri, na ihe mgbakwunye nri, n'ihi uru ahụike na ojiji ya n'ịkwalite metabolism ike.
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2′-Deoxycytidine CAS:951-77-9
2′-Deoxycytidine bụ nucleoside nke mejupụtara shuga deoxyribose na cytosine, nke a na-ahụ site na enweghị otu hydroxyl na ọnọdụ 2′ nke ribose. Mgbanwe a na-eme ka ọ bụrụ akụkụ dị mkpa nke DNA, ebe ọ na-ejikọ ya na guanine n'oge njikọta ntọala. 2′-Deoxycytidine na-arụ ọrụ dị mkpa na metabolism cellular na njikọ DNA, na-eje ozi dị ka ihe owuwu maka deoxycytidine triphosphate (dCTP), nke dị mkpa maka mmegharị na ndozi DNA. Na mgbakwunye, nucleoside a nwere mmetụta dị mkpa na nyocha bayọlọji, ọgwụgwọ kansa, na atụmatụ mgbochi nje, na-egosipụta mkpa ọ dị na ma nyocha bụ isi na ngwa ahụike.
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2,2′-cyclouridine CAS:3736-77-4
2,2′-Cyclouridine bụ ihe e si na uridine nweta nuklioside bicyclic, nke a na-ahụ site na ịmepụta usoro cyclic pụrụ iche nke gụnyere ọnọdụ 2′ na 2” nke ribose. Mgbanwe nhazi a na-enye ihe pụrụ iche dị na biochemical nke na-emetụta nkwụsi ike ya na ọrụ bayoloji. 2,2′-Cyclouridine enwetawo mmasị na bayoloji kemịkalụ na kemistri ọgwụ n'ihi ojiji ya dị ka ihe na-egbochi nje na nyocha RNA. Ike ya ịhazi mmekọrịta nucleic acid na-eme ka ọ bụrụ ngwaọrụ bara uru maka ịmụ mmekọrịta nhazi RNA na ọrụ, nke nwere ike ibute ọganihu na atụmatụ ọgwụgwọ na-elekwasị anya na ọrịa nje na ọrịa mkpụrụ ndụ ihe nketa.
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2-Aminoadenosine CAS:2096-10-8
2-Aminoadenosine bụ ihe sitere n'okike nke adenosine, nke a na-ahụ site na ọnụnọ nke otu amino na ọnọdụ abụọ nke shuga ribose. Mgbanwe a na-agbanwe njirimara na ọrụ ya nke ukwuu, na-eme ka ọ bụrụ molekul dị mkpa na usoro physiological dị iche iche. 2-Aminoadenosine na-etinye aka na mgbaama sel, metabolism, na ụzọ nchịkwa, gụnyere ndị metụtara homeostasis ike na neurotransmission. Ngwa ọgwụgwọ ya nwere ike ịgbasa n'ọtụtụ ubi, gụnyere neurobiology na cardiology, ebe ọ nwere ike imetụta nzaghachi sel na nrụgide na mmerụ ahụ. Ka nnyocha na-aga n'ihu, 2-aminoadenosine nwere nkwa maka ịmepụta ogige bioactive ọhụrụ na ihe ndị na-agwọ ọrịa.
