Fmoc-Asp(OBut)-OSu CAS:78553-23-8

Fmoc-Asp(OBut)-OSu na-eje ozi dị ka ngwa ọrụ dị iche iche na mmepụta peptide, ọkachasị n'ịmepụta peptides nwere aspartic acid na nkenke. Otu nchekwa Fmoc na-echebe otu amino, na-ahụ na mmeghachi omume nhọrọ n'oge njikọ peptide, ebe otu O-butyl na-agbakwunye oyi akwa nchekwa ọzọ na otu carboxyl. Ọrụ OSu ester na-eme ka nhazi njikọ amide dị irè ma dị mma n'oge mmeghachi omume njikọ peptide. Ndị nchọpụta na-eji Fmoc-Asp(OBut)-OSu nke ukwuu na imepụta peptides maka ngwa dị iche iche, gụnyere mmepe ọgwụ, ihe ndị dị ndụ, na imepụta peptides bioactive nwere atụmatụ nhazi pụrụ iche. Ndakọrịta ya na usoro njikọta peptide ọkọlọtọ, ma na usoro siri ike na usoro ngwọta, na-eme ka ọ dịkwuo mma na mgbalị nyocha dị iche iche. Mwepụ a na-achịkwa nke otu nchekwa na-enye ohere itinye aspartic acid n'usoro peptide, na-agbasa oke nke peptides synthesizable. Ọzọkwa, Fmoc-Asp(OBut)-OSu na-achọta uru na nhazi peptides maka nyocha proteomics na ịmụ usoro sel. Ojiji atụmatụ nke otu nchekwa O-butyl na-eme ka a na-emegharị mmeghachi omume aspartic acid nke ọma, otu OSu ester na-emekwa ka bioconjugation na labeling nke peptides dị mfe. Na nchịkọta, Fmoc-Asp(OBut)-OSu na-eguzo dị ka ngwa ọrụ dị mkpa na kemistri peptide, na-enye ndị nchọpụta ike inyocha na ịgbanwe mmeghachi omume aspartic acid maka ọtụtụ ngwa sayensị, ọkachasị ilekwasị anya na peptides nwere ọrụ ka mma site na otu OSu ester.