Leflunomide CAS:75706-12-6 Onye Na-eweta Ngwaahịa

Leflunomide bụ ọgwụ na-ebelata ọrịa nke a na-ere n'ọnụ, a na-emepụtakwa ya dị ka Arava na US maka ọgwụgwọ ọrịa ogbu na nkwonkwo (RA); ọ bụ naanị ọgwụ mbụ a tụrụ aro iji belata mmebi nkwonkwo nke RA, yabụ na-edozi mkpa ahụike na-anaghị emezu. Leflunomide bụ ọgwụ na-eme ka ọ dị ngwa ngwa ma fọrọ nke nta ka ọ bụrụ kpamkpam (ọkara ndụ, ihe na-erughị nkeji iri isii) mgbe ejiri ya n'ọnụ nye teriflunomide, metabolite α-cyanoenol na-arụ ọrụ nke ọma na ọgwụ.

Nye iwu ma ọ bụ rịọ maka ọnụahịa

Nkọwa Ngwaahịa

Akara Ngwaahịa

Ngwa na Mmetụta

Leflunomide anaghị arụ ọrụ, mana teriflunomide na-egbochi njikọ pyrimidine de novo na obere ọgwụ ọgwụgwọ site na igbochi dihydrorotate dehydrogenase (enzyme na-ekpebi ọnụego maka njikọta nke UMP), na-ebelata njikọ DNA na RNA, ma na-egbochi usoro mmụba nke mkpụrụ ndụ na mmepụta nke ọgwụ mgbochi. Mbelata nke dihydrorootate ka ọ bụrụ orotate na-eme n'otu oge na mbelata nke cofactor ya, ubiquinone (coenzyme Q). Mgbochi nke dihydrorootate dehydrogenase site na teriflunomide na-egosi kinetics na-abụghị asọmpi na nke na-abụghị asọmpi. Ntinye leflunomide n'ime ndị ọrịa nwere ọrịa ogbu na nkwonkwo na-eme ka mwepụ nke mkpụrụ ndụ B na-aga n'ihu na mbelata nke usoro ahụ ji alụso ọrịa ọgụ.

Ihe Nlereanya Ngwaahịa

Nkwakọ ngwaahịa:

Ozi Mgbakwunye:

Ihe mejupụtara ya	C12H9F3N2O2
Nnwale	99%
Ọdịdị	Ntụ ntụ ọcha
Nọmba CAS	75706-12-6
Nkwakọ ngwaahịa	25KG
Ndụ nchekwa	afọ 2
Nchekwa	Debe n'ebe dị jụụ ma kpọọ nkụ
Asambodo	ISO.