Losartan Potassium CAS:124750-99-8 Onye Na-eweta Ngwaahịa

Losartan potassium bụ ọgwụ mbụ nwere ike ma na-ahọrọ nke na-abụghị peptide angiotensin II (AT II) AT1 nke ewepụtara n'ahịa dị ka ọgwụ mgbochi ọbara mgbali elu nke a na-aṅụ otu ugboro kwa ụbọchị. Ọ dị irè ma na-adịgide ogologo oge n'ịchịkwa ọbara mgbali elu na oke ndị nwere ọbara mgbali elu, na ndị ọrịa nwere ọbara mgbali elu dị mkpa yana ndị ọrịa nwere nsogbu akụrụ. E wezụga nke ahụ, nnyocha e mere n'oge na-adịbeghị anya egosila na losartan bara uru iji weghachite nsogbu afọ n'ịnọgide na-enwe ọbara mgbali elu nkịtị na ojiji ike sel na mitochondria, enwere ike iji ya gwọọ hypertrophy ventricular aka ekpe. Enwere ike iji ya dị ka ọgwụ ọzọ maka ọgwụgwọ nke nsogbu systolic, infarction myocardial, ọrịa akwara obi, na nkụda obi.