Mirabegron CAS: 223673-61-8 Onye na-ebuputa ihe onyonyo egosipụtara

Mirabegron CAS: 223673-61-8 Onye na-emepụta ihe

Mirabegron bụ maka ọgwụgwọ ngwa ngwa, ugboro ole urinary, na mmamịrị mmamịrị na-adịghị akwụsị akwụsị nke jikọtara ya na eriri afo na-emebiga ihe ókè (OAB).A na-emepụta Mirabegron site na ijikọta 4-nitrophenethyl amine na (R) -2-hydroxy-2-phenylacetic acid.A na-ebelata amide nke na-esi na ya pụta na amine.A na-ebelata ìgwè nitro ahụ, ihe si na ya pụta na-ejikọta ya na 2- (2-aminothiazol-4-yl) acetic acid iji nye mirabegron.

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Mirabegron bụ β3-adrenoceptor agonist na-arụ ọrụ ugbu a site na Astellas Pharma maka ọgwụgwọ nke eriri afo na-adịghị arụ ọrụ (OAB).Ọgwụ a bụ onye na-emegide EC50 nanomolar megide nyocha biochemical nke mmadụ β3-AR nwere ezigbo nhọrọ karịa b1- na β2-AR.Mirabegron na-egosiputa usoro ọhụụ site n'ịchụso β3-AR maka izu ike nke eriri afo iji nyere aka jikwaa mgbaàmà OAB dị ka mmụba mmamịrị ngwa ngwa na ugboro ugboro na nkwụsị ngwa ngwa.Agbanyeghị, mirabegron bụ onye na-egbochi cytochrome P450 2D6, ọ na-ebulitekwa nchegbu maka mmekọrịta ọgwụ-ọgwụ yana nchịkwa cytochrome P450 2D6 ndị ọzọ.

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Ozi Mgbakwunye:

Ihe mejupụtara	C21H24N4O2S
Nyocha	99%
Ọdịdị	Ọcha na-acha odo odo ntụ ntụ
CAS Mba.	223673-61-8
Nkwakọ ngwaahịa	25KG
Ndụ shelf	afọ 2
Nchekwa	Chekwaa na ebe dị jụụ na nke akọrọ
Asambodo	ISO.