Mirabegron CAS:223673-61-8 Onye Na-eweta Ngwaahịa

A na-eji Mirabegron agwọ ọrịa ngwa ngwa, ugboro ugboro nke mmamịrị, na nsogbu mmamịrị nke metụtara oke ọrụ akụrụ (OAB). A na-emepụta Mirabegron site na ijikọ 4-nitrophenethyl amine na (R)-2-hydroxy-2-phenylacetic acid. A na-ebelata amide nke na-esi na ya apụta ka ọ bụrụ amine. A na-ebelata otu nitro ahụ ma jikọta ihe si na ya pụta na 2-(2-aminothiazol-4-yl) acetic acid iji nye mirabegron.

Nye iwu ma ọ bụ rịọ maka ọnụahịa

Nkọwa Ngwaahịa

Akara Ngwaahịa

Ngwa na Mmetụta

Mirabegron bụ β3-adrenoceptor agonist nke na-arụ ọrụ ọnụ ugbu a site n'aka Astellas Pharma maka ọgwụgwọ nke eriri afọ na-arụsi ọrụ ike (OAB). Ọgwụ a bụ antagonist nanomolar EC50 megide nyocha biochemical β3-AR mmadụ nwere ezigbo nhọrọ karịa b1- na β2-ARs. Mirabegron na-egosi usoro ọhụrụ site na ilekwasị anya na β3-AR maka izu ike eriri afọ iji nyere aka jikwaa mgbaàmà OAB dịka mmụba nke ngwa ngwa mmamịrị na ugboro ugboro na enweghị ike ịchịkwa ngwa ngwa. Agbanyeghị, mirabegron bụ cytochrome P450 2D6 na-egbochi, ọ na-akpalikwa nchegbu maka mmekọrịta ọgwụ na ọgwụ na ojiji nke ihe ndị ọzọ cytochrome P450 2D6.

Ihe Nlereanya Ngwaahịa

Nkwakọ ngwaahịa:

Ozi Mgbakwunye:

Ihe mejupụtara ya	C21H24N4O2S
Nnwale	99%
Ọdịdị	Ntụ ntụ ọcha ruo na-acha odo odo
Nọmba CAS	223673-61-8
Nkwakọ ngwaahịa	25KG
Ndụ nchekwa	afọ 2
Nchekwa	Debe n'ebe dị jụụ ma kpọọ nkụ
Asambodo	ISO.