PhentolamineMesylate CAS:65-28-1

Phentolamine mesylate na-arụ ọrụ dị iche iche dị mkpa n'ọrụ ọgwụgwọ na nyocha. Dịka ọgwụ vasodilator siri ike na ọgwụ mgbochi ọbara mgbali elu, a na-eji ya agwọ ọrịa mberede ọbara mgbali elu, ọkachasị n'ihe gbasara nsogbu pheochromocytoma, ebe mbelata ọbara mgbali elu ngwa ngwa dị mkpa. Ọ na-ahụkwa uru n'ịchịkwa ọrịa ọbara mgbali elu nke catecholamine kpatara n'oge usoro ịwa ahụ na ọgwụgwọ ndị ọzọ. Na ezé ezé, a na-eji phentolamine mesylate eme ihe dị ka ọgwụ mgbu mpaghara, na-enyere aka na njikwa nke anesthesia anụ ahụ dị nro mgbe usoro ezé gụnyere ọgwụ mgbu mpaghara nwere vasoconstrictor dị ka epinephrine. Mmetụta vasodilatory ya na-enyere aka ibelata mmachi ọbara mpaghara ma na-eme ka mgbake nke perfusion anụ ahụ nkịtị dịkwuo ngwa ngwa. Ọzọkwa, a na-eji ngwakọta a eme ihe na usoro nchọpụta dịka mgbochi na ọgwụgwọ nke necrosis akpụkpọ ahụ nke sitere na extravasation nke ọgwụ vasoactive, na-ahụ na perfusion anụ ahụ kwesịrị ekwesị. Na mgbakwunye, ọ na-etinye aka na ọmụmụ ihe na nnwale ụlọ ọgwụ na-enyocha ojiji ya nwere ike na ọnọdụ metụtara enweghị ike vascular, nsogbu erectile, na ihe Raynaud's phenomena, na-enye aka na ọganihu na ọgwụ obi na urological. Ọrụ Phentolamine mesylate na-aga n'ihu na ntọala nnwale dị ka ngwa ọrụ na nyocha ọgwụ na ahụike, na-enyere aka na nyocha nke ọrụ adrenergic receptor, nzaghachi akwara, na mgbanwe nke ọrụ sistemụ akwara ọmịiko. Ike ya igbochi ndị na-anabata adrenergic na imetụta ụda akwara na-enyere aka na nghọta nke physiology obi na mmepe nke ọgwụgwọ ndị na-elekwasị anya na ụzọ mgbaàmà adrenergic. N'ozuzu, ngwa dị iche iche nke phentolamine mesylate na-egosipụta mkpa ọ dị na ọgwụ ahụike, ezé, nyocha, na mmepe ọgwụ, na-egosi ike ya itinye aka na njikwa dị irè nke ọnọdụ obi na ọganihu nke ihe ọmụma sayensị metụtara ọrụ receptor adrenergic na nhazi akwara.