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N, N-Bis (2-hydroxyethyl) -2-aminoethanesulfonic acid sodium nnu CAS: 66992-27-6
N, N-Bis (2-hydroxyethyl) -2-aminoethanesulfonic acid sodium nnu, nke a makwaara dị ka HEPES sodium salt, bụ ngwakọta kemịkalụ nke a na-ejikarị dị ka onye na-ebufe pH na ụlọ nyocha nke ndu na kemịkal.Ọ na-enyere aka ịnọgide na-enwe pH kwụsiri ike, na-eme ka ọ dị mma maka ngwa dị ka omenala cell, nyocha enzyme, ọmụmụ protein, electrophoresis, na usoro ọgwụ.HEPES sodium nnu na-eme ka ọnọdụ dị mma maka usoro ndu ma kwalite izi ezi na ntụkwasị obi nke nsonaazụ nnwale.
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2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM SALT CAS:76204-02-9
2'- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid sodium salt bụ ngwakọta kemịkalụ nke a na-ejikarị eme nchọpụta na nyocha nyocha.Ọ bụ sialic acid nke akpọrọ fluorescently, ụdị molekul carbohydrate dị n'elu sel.
A na-eji ogige a mee ihe dị ka ihe ntinye maka enzymes a na-akpọ neuraminidases, nke na-eme ka wepụ sialic acid residues na glycoproteins na glycolipids.Mgbe enzymes ndị a na-arụ ọrụ na 2'- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid sodium salt, ọ na-ahapụ ngwaahịa fluorescent mara dị ka 4-methylumbelliferone.
Enwere ike tụọ fluorescence nke ogige ahụ na-emepụta na ọnụ ọgụgụ ya, na-enye ozi gbasara ọrụ nke neuraminidase enzymes.Nke a bara uru karịsịa n'ịmụ ọrịa dị iche iche na ọnọdụ ndị metụtara aberrant sialic acid metabolism.
A na-ejikwa ogige ahụ maka ebumnuche nyocha, dị ka n'ịchọpụta ọrịa nje na-agụnye ọrụ neuraminidase.N'ime nyocha ndị a, a na-eji ogige ahụ chọpụta ọnụnọ nke ụdị nje virus dị iche iche ma ọ bụ chọpụta irè nke neuraminidase inhibitors na ọgwụgwọ antiviral.
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TAPSO CAS: 68399-81-5 Onye nrụpụta ọnụahịa
TAPSO (3-[N-tris(hydroxymethyl)methyl]amino]-2-hydroxypropanesulfonic acid) bụ ihe nchekwa zwitterionic nke a na-ejikarị na nyocha nke ndu na biochemical.Ọ bụ onye na-echekwa ihe na-arụ ọrụ nke ọma yana pKa dị nso na pH physiological, na-eme ka ọ dị mma maka idowe pH kwụsiri ike na nnwale nke ndu.A na-ejikarị TAPSO eme ihe na-edozi protein, nyocha enzyme, omenala cell, na ngwa electrophoresis.Nnukwu mmiri solubility ya na nnyonye anya dị ala na usoro ndu na-eme ka ọ bụrụ nhọrọ a ma ama na obodo sayensị.A maara TAPSO maka ntakịrị mmetụta ya na ọrụ enzyme ma a na-ejikarị ya eme ihe dị ka ihe ọzọ na-ebufe ndị ọzọ dị ka Tris ma ọ bụ phosphate buffers.
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N-Acetyl-L-cysteine CAS: 616-91-1
N-Acetyl-L-cysteine (NAC) bụ ụdị nke amino acid cysteine gbanwetụrụ.Ọ na-enye isi iyi nke cysteine ma nwee ike ịtụgharị ngwa ngwa na tripeptide glutathione, antioxidant siri ike n'ime ahụ.A maara NAC maka akụrụngwa antioxidant na mucolytic, na-eme ka ọ baa uru na ngwa ahụike dị iche iche.
Dị ka antioxidant, NAC na-enyere aka ichebe mkpụrụ ndụ site na mmebi nke radicals free, ụdị oxygen na-emeghachi omume, na nsị.Ọ na-akwadokwa njikọ glutathione, nke na-arụ ọrụ dị oke mkpa na usoro nsị nke anụ ahụ yana idowe usoro ahụ ji alụso ọrịa ọgụ dị mma.
A mụọla NAC maka uru ọ nwere na ahụike iku ume, ọkachasị ndị nwere ọnọdụ dịka bronchitis na-adịghị ala ala, COPD, na cystic fibrosis.A na-ejikarị ya eme ihe dị ka ihe na-atụ anya iji nyere aka dị nro na ịtọpụ imi, na-eme ka ọ dịkwuo mfe ikpochapụ okporo ụzọ ikuku.
Ọzọkwa, NAC egosila nkwa n'ịkwado ahụike imeju site n'inyere aka n'iwepụ ihe ndị na-egbu egbu, dị ka acetaminophen, ihe na-ebelata mgbu.O nwekwara ike inwe mmetụta nchebe megide mmebi imeju nke ịṅụ mmanya na-aba n'anya kpatara.
Na mgbakwunye na akụrụngwa nkwado nke antioxidant na iku ume, NAC enyochala maka uru ọ nwere na ahụike uche.Ụfọdụ nnyocha na-egosi na ọ nwere ike inwe mmetụta dị mma na nsogbu ọnọdụ uche, dị ka ịda mbà n'obi na nsogbu mgbagwoju anya (OCD).
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PIPES CAS: 5625-37-6 Onye nrụpụta ọnụahịa
PIPES (piperazine-1,4-bisethanesulfonic acid) bụ ihe nkpuchi zwitterionic a na-ejikarị na nyocha nke ndu na biochemical.Ọ bụ ihe nchekwa pH dị irè nke nwere ikike dị elu maka idowe ọnọdụ pH kwụsiri ike na pH nke 6.1 ruo 7.5.PIPES nwere obere nnyonye anya na biomolecules ma dabara adaba maka nyocha dabere na ọnọdụ okpomọkụ.A na-ejikarị ya eme ihe na usoro electrophoresis gel na usoro ọgwụ dị ka onye na-eme ka ahụ sie ike.N'ozuzu, PIPES bụ ngwakọta na-ejikarị eme ihe na ntọala nnwale dị iche iche.
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2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridiniuM-9-carboxylate 4′-NHS Ester CAS:194357-64-7
2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4′-NHS ester bụ ngwakọta kemịkalụ nwere usoro ihe omimi dị mgbagwoju anya.Ọ nwere otu sulfopropylacridinium na otu carboxylate ester na-arụ ọrụ.Ọnụnọ nke moiety ester na-egosi na ọ na-emeghachi omume na enwere ike iji ya dị ka akara ma ọ bụ na-agbanwe agbanwe maka biomolecules.
Otu sulfopropylacridinium nke ogige ahụ na-atụ aro na ọ nwere ike ịnwe ngwa ngwa na nyocha nke dabere na fluorescence, ebe enwere ike iji ya dị ka nyocha fluorescent ma ọ bụ ihe esiji maka ịchọpụta na nyochaa biomolecules.Ọ nwekwara ike ịba uru na ọmụmụ ihe gbasara usoro cellular, dị ka nrịbama calcium intracellular.
Ntinye nke otu NHS ester na-egosi na ọ nwere ike meghachi omume na amines ndị bụ isi, dị ka ndị ahụ dị na protein ma ọ bụ peptides, iji mepụta njikọ amide kwụsiri ike.Nmeghachi omume a na-eme ka ọ baa uru maka ngwa bioconjugation, ebe enwere ike iji akara ma ọ bụ gbanwee biomolecules na ụmụ irighiri ihe ndị ọzọ na-arụ ọrụ, dị ka fluorophores ma ọ bụ mkpado.
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5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide CAS:4264-82-8
5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide bụ ngwakọta a na-eji n'ọmụmụ ihe ọmụmụ biochemical dị iche iche, ọkachasị maka nchọpụta na nhụta ọrụ enzyme.Ọ bụ mkpụrụ nke nwere ike ịmegharị ya site na enzymes kpọmkwem, na-ebute ntọhapụ nke ngwaahịa agba ma ọ bụ fluorescent.
A na-ejikarị ọgwụ a eme ihe na nyocha iji chọpụta ọnụnọ na ọrụ nke enzymes dị ka beta-galactosidase na beta-glucuronidase.Enzymes ndị a na-ekewa ndị acetyl na glucosaminide site na mkpụrụ, na-eduga n'ichebe chromophore na-acha anụnụ anụnụ ma ọ bụ akwụkwọ ndụ akwụkwọ ndụ.
Ọdịdị pụrụ iche nke 5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide na-enye ohere maka nchọpụta dị mfe na ọnụọgụ ọrụ enzyme.Ojiji ya na usoro nnwale dị iche iche, gụnyere histochemistry, immunohistochemistry, na nyocha nke sitere na cell, enyela aka na nghọta ka mma nke ọrụ enzyme.
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Nnu nnu sodium CAS: 139-41-3 Onye nrụpụta ọnụahịa
N, N-Bis (2-hydroxyethyl) glycine sodium nnu bụ ngwakọta kemịkalụ ejiri dị ka onye na-echekwa ihe na ngwa biochemical dị iche iche na biophysical.Ọ na-enyere aka ịnọgide na-enwe ọkwa pH kwụsiri ike na ọnọdụ nnwale, na-eme ka ọ baa uru na ọmụmụ enzyme, nchọpụta protein, omenala cell, na usoro nkwụsị nke Western.
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Spinosad CAS: 131929-60-7 Onye na-ebupụta ihe
Spinosad bụ otu 5 nicotinic acetylcholine agonist receptor agonist, nke na-ebute mkpụkọ akwara na-achọghị onwe ya na ịma jijiji nke abụọ na-arụ ọrụ neuron moto.Mkpughe ogologo oge na-akpata ahụ mkpọnwụ na anwụ anwụ.Ọnwụ anwụ na-amalite n'ime nkeji 30 nke doses na n'ime awa 4 zuru ezu.Spinosad anaghị emekọrịta na saịtị njikọ nke ndị na-ahụ maka ụmụ ahụhụ ndị ọzọ (GABA-ergic ma ọ bụ nicotinic).
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Rotenone CAS: 83-79-4 Onye na-emepụta ihe
Rotenone bụ ma afo na kọntaktị nsi maka arthropods.A na-ekwu na ọ na-eme ngwa ngwa ịkụda mmụọ ya n'ihi ibelata nnweta nicotinamide adenine dinucleotide ka ọ bụrụ onye na-emekọ ihe n'ụzọ dị iche iche nke biochemical gụnyere okirikiri Krebs, si otú a na-egbochi enzymes iku ume mitochondrial.
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Diazinon CAS: 333-41-5 Onye na-emepụta ihe
Diazinon dị n'ụdị mmiri mmiri na-enweghị agba ma ọ bụ ọchịchịrị gbara ọchịchịrị.Ọ na-agbaze obere oge na mmiri mana ọ na-agbaze nke ukwuu na ether petroleum, mmanya na benzene.A na-eji Diazinon chịkwaa ụdị ọrụ ugbo dị iche iche na ụmụ ahụhụ ezinụlọ.Ndị a na-agụnye ụmụ ahụhụ na ala, na osisi ịchọ mma, mkpụrụ osisi, akwụkwọ nri, na ihe ọkụkụ na ụmụ ahụhụ ezinụlọ dị ka ijiji, fleas, na ọchịcha.
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Avermectin CAS: 71751-41-2 Onye na-emepụta ihe
Abamectin (Avermectin) bụ ihe na-egbu egbu.Usoro ya na-elekwasị anya na onye na-anabata GABAA nke ụmụ ahụhụ neuron synapse ma ọ bụ neuromuscular synapse, na-etinye aka na nnyefe ozi nke njedebe akwara, ya bụ na-akpali njedebe akwara iji hapụ onye na-eme ihe nchịkwa neurotransmitter γ-aminobutyric acid (GA-BA), na-eme ka oghere dị ukwuu nke oghere ahụ. Ọwa chloride GABA nwere mmetụta na-arụ ọrụ ọwa chloride.
