R-(+)-alpha-Lipoic acid CAS:1200-22-2 Onye Na-eweta Ngwaahịa

A hụrụ na R-(+)-α-Lipoic acid na-eme ka pyruvate oxidation dịkwuo elu ma na-ewepụ oxidation nke abụba na hepatocytes oke. Mmetụta ndị a na-eme ka R-(+)-α-Lipoic acid bụrụ nhọrọ ọgwụgwọ na-ekwe nkwa maka ọgwụgwọ nke ọrịa shuga Ụdị nke Abụọ. Ọ bụ antioxidant bayọlọji nwere ọrụ prooxidant, a na-enyocha ike ọgwụgwọ ya nke ọma, dịka ọmụmaatụ na ọgwụgwọ maka ọrịa Alzheimer. Ejirila α-Lipoic acid dị ka ọkọlọtọ ntụaka maka nyocha nke α-lipoic acid na plasma mmadụ site na chromatography mmiri mmiri arụmọrụ dị elu jikọtara ya na electron capture detector (HPLC-ECD), na ọtụtụ nri matrices na mgbakwunye nri site na HPLC yana coulometric electrode array detector (CEAD) yana electrospray ionization mass spectrometer (ESI-MS). Enwere ike iji ya dị ka ọkọlọtọ ntụaka maka mkpebi nke α-lipoic acid na mmamịrị mmadụ site na isocratic reversed-phase HPLC na na α-lipoic acid capsules site na HPLC na nchọpụta chemiluminescence.