Simvastatin CAS:79902-63-9 Onye Na-eweta Ngwaahịa

Simvastatin bụ ihe na-eme ka mmadụ ghara inwe mmetụta ọjọọ, ọ na-emekwa ka mmadụ ghara inwe mmetụta ọjọọ, dịka ihe atụ nke lovastatin. Dịka lovastatin, simvastatin bụ ihe na-egbochi HMG-CoA reductase ma a na-eji ya agwọ ọrịa iji belata cholesterol LDL. N'oge na-adịbeghị anya, statins aghọọla ihe dị mkpa na biochemical probes na biology. Enwere ike ijikọ ha na ọtụtụ ihe omume na ụzọ mbụ ha si arụ ọrụ, mana usoro nke ọtụtụ mmetụta ndị ọzọ adịghị apụta ìhè. Simvastatin bụ ihe na-egbochi HMG-CoA reductase kpọmkwem, enzyme nke na-akwalite mgbanwe nke HMG-CoA ka ọ bụrụ mevalonate, nke bụ nzọụkwụ mbụ na cholesterol biosynthesis. A na-eji ya agwọ hypercholesterolemia, ebe ọ na-ebelata ọkwa nke obere lipoproteins na triglycerides, ma na-ebuli ọkwa lipoprotein dị elu.