1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carbonitrile CAS:2158267-70-8

1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carbonitrile na-arụ ọrụ dị mkpa dị ka ihe etiti na njikọta nke ogige ndị dị mgbagwoju anya, bioactive nwere ike iji ọgwụ. Ntinye ya na usoro molekul na-enyere ndị nchọpụta aka inyocha ndị na-achọ ọgwụ ọhụrụ na-elekwasị anya na mpaghara ọgwụgwọ dị iche iche dịka ndị na-egbochi kinase, nyocha fluorescent, ma ọ bụ ngwa kemistri ihe. Ọnụnọ nke isi pyrazole na otu dioxaborane na-ewebata mmeghachi omume kpọmkwem na ihe ndị na-enye ọgwụ, na-eme ka ọ baa uru maka nyocha kemistri ọgwụ. Na mbọ nchọpụta ọgwụ, ihe a nwere ike ịbụ ebe mmalite maka imepụta ndị nwere ike inweta ọgwụ, na-eji atụmatụ nhazi ya emeziwanye ọrụ bayoloji na ihe ndị na-enye ọgwụ. Na mgbakwunye, otu ọrụ dioxaborane na-enye ohere maka mmepụta ọzọ na kemistri njikọta, nke nwere ike ibute mmepe nke molekul ọhụrụ nwere ihe ndị na-enye ndụ dị mma na profaịlụ pharmacokinetic ka mma. Ọzọkwa, n'ebe agụmakwụkwọ na ụlọ ọrụ mmepụta ihe, ndị nchọpụta nwere ike iji ihe owuwu a kwadebe ọbá akwụkwọ nke ihe dị iche iche maka ọmụmụ mmekọrịta nhazi na ọrụ, na-eme ka ọ dị mfe ịchọpụta ihe ndị nwere mmetụta dị ndụ achọrọ. Ọrụ ya na mmepụta kemịkalụ na-agbatị ruo n'ịmepụta ihe ndị na-emepụta ọgwụ na mmepe nke usoro mmepụta ọhụrụ, na-egosipụta uru ya sara mbara n'ofe ngalaba sayensị. N'ozuzu, 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-3-carbonitrile na-arụ ọrụ dị mkpa n'ịchụso nchọpụta ọgwụ ọhụrụ na nyocha kemịkalụ, na-enye ikpo okwu maka mmepe nke ọtụtụ molekul na-arụ ọrụ na bayoloji na ihe ndị na-emepụta ọgwụ.