4-Nitrophenyl Beta-D-glucuronide CAS: 10344-94-2

Nchọpụta ọrụ β-glucuronidase: 4-NPBG na-ejikarị dị ka mkpụrụ chromogenic iji chọpụta ọnụnọ na ọrụ nke β-glucuronidase n'ụdị ụdị ndu dị iche iche.Enzyme ahụ na-ekewa njikọ glycosidic nke 4-NPBG, na-emepụta 4-nitrophenol, nke enwere ike tụọ ya site na iji spectrophotometry.

Ọmụmụ metabolism ọgwụ: Ebe β-glucuronidase na-arụ ọrụ dị mkpa na metabolism nke ọgwụ na xenobiotics, enwere ike iji 4-NPBG nyochaa ọrụ nke enzyme a na ọmụmụ metabolism ọgwụ.Ọ na-enyere aka ịghọta oke na kinetics nke mmeghachi omume glucuronidation, nke dị mkpa maka mkpochapụ ọgwụ na bioavailability.

Ọmụmụ toxicology: Ụfọdụ ogige toxicological nwere ike metabolized ma wepụ ya n'ụdị glucuronide conjugates.Site na iji 4-NPBG dị ka mkpụrụ, ndị na-eme nchọpụta nwere ike nyochaa ọrụ β-glucuronidase na anụ ahụ dị iche iche ma ọ bụ ahịrị sel iji nyochaa ihe nwere ike ịdị nsi ma ọ bụ mmetụta ọjọọ nke ogige.

Nchọpụta nyocha ụlọ ọgwụ: Enwere ike iji nha nke ọrụ β-glucuronidase na-eji 4-NPBG na ntọala ụlọ ọgwụ iji chọpụta ọrịa ụfọdụ ma ọ bụ ọnọdụ.Ọkwa dị njọ ma ọ bụ ọrụ β-glucuronidase nwere ike igosi ụfọdụ ọrịa mkpụrụ ndụ ihe nketa, arụ ọrụ imeju, ma ọ bụ kansa.