Candesartan CAS: 139481-59-7 Onye na-ebupụta ihe onyonyo egosipụtara

Candesartan CAS: 139481-59-7 Onye na-emepụta ihe

Candesartan bụ angiotensin II receptor I (AT1) antagonist, IC50s = 1.12 na 2.86 nM maka bovine adrenal cortex na oke bekee aorta n'otu n'otu. , KCl, serotonin, PGF2a ma ọ bụ endothelin.

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Ngwa na Mmetụta

Candesartan bụ onye na-emegide AT1 (angiotensin II receptor 1).Antagonism nke ndị na-anabata angiotensin na-egbochi vasoconstriction na mmepụta nke aldosterone, na-eduga mbelata mmiri na ntinye sodium na plasma ọbara.Na-egosipụta mmetụta antihypertensive na ụdị anụmanụ.A na-eji ya na ọgwụgwọ nke nkụda mmụọ obi, dị ka antihypertensive.Candesartan anaghị emetụta ndụ mkpụrụ ndụ ma ọ bụ mmụba mana ọ na-abawanye nkwupụta nke VEGF na interleukin-8 na usoro omenala nke sel KU-19-19.Candesartan (0.1 nM) nwere ike ibelata nzaghachi nkwekọrịta kachasị na angiostensin II site na ihe dịka 50%.

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Ihe mejupụtara	C24H20N6O3
Nyocha	99%
Ọdịdị	Ọcha ntụ ntụ
CAS Mba.	139481-59-7
Nkwakọ ngwaahịa	1KG 25KG
Ndụ shelf	afọ 2
Nchekwa	Chekwaa na ebe dị jụụ na nke akọrọ
Asambodo	ISO.