Candesartana Cilexetila CAS:145040-37-5

Candesartan cilexetil bụ ọgwụ nke onye na-emegide angiotensin II nke nwere ike, ogologo oge, na nhọrọ AT1, candesartan. A na-agbanwe ya ngwa ngwa ka ọ bụrụ candesartan n'oge a na-anabata eriri afọ. Mgbe a gbasasịrị candesartan cilexetil na candesartan n'oge a na-anabata eriri afọ, candesartan na-asọmpi na angiotensin II maka njikọ nke angiotensin II receptor subtype 1 AT1 na akwara dị nro nke vascular, na-egbochi vasoconstriction nke angiotensin II na-akwalite ma na-akpali vasodilatation. Na mgbakwunye, mmegide nke AT1 na gland adrenal na-egbochi njikọ aldosterone nke angiotensin II na-akpali na mwepụta site na adrenal cortex; sodium na mmiri na-abawanye, na-esochi mbelata na olu plasma na ọbara mgbali.