Candesartan CAS:139481-59-7 Onye Na-eweta Ngwaahịa

Candesartan bụ ihe na-egbochi angiotensin II receptor I (AT1), IC50s=1.12 na 2.86 nM maka cortex adrenal ehi na aorta rabbit n'otu n'otu. Na-egbochi nkwụsịtụ nke angiotensin II nke eriri aortic rabbit kpatara na-enweghị mmetụta ọ bụla na nkwụsịtụ nke ihe ndị ọzọ dịka norepinephrine, KCl, serotonin, PGF2α ma ọ bụ endothelin kpatara.

Nye iwu ma ọ bụ rịọ maka ọnụahịa

Nkọwa Ngwaahịa

Akara Ngwaahịa

Ngwa na Mmetụta

Candesartan bụ ihe na-egbochi AT1 (angiotensin II receptor 1) nke a họọrọ. Mmegide nke ndị na-anabata angiotensin na-egbochi vasoconstriction na mmepụta nke aldosterone, na-eduga na mbelata na ntinye mmiri na sodium na plasma ọbara. Ọ na-egosipụta mmetụta mgbochi ọbara mgbali elu na ụdị anụmanụ. A na-eji ya agwọ ọrịa obi na-akpata mkpọchi, dị ka ọgwụ mgbochi ọbara mgbali elu. Candesartan anaghị emetụta ndụ sel ma ọ bụ mmụba kama ọ na-eme ka ngosipụta nke VEGF na interleukin-8 dịkwuo elu na usoro ọdịbendị nke mkpụrụ ndụ KU-19-19. Candesartan (0.1 nM) nwere ike ibelata nzaghachi nkwekọrịta kachasị na angiostensin II site na ihe dị ka 50%.

Ihe Nlereanya Ngwaahịa

Nkwakọ ngwaahịa:

Ozi Mgbakwunye:

Ihe mejupụtara ya	C24H20N6O3
Nnwale	99%
Ọdịdị	Ntụ ntụ ọcha
Nọmba CAS	139481-59-7
Nkwakọ ngwaahịa	1KG 25KG
Ndụ nchekwa	afọ 2
Nchekwa	Debe n'ebe dị jụụ ma kpọọ nkụ
Asambodo	ISO.