Candesartana Cilexetila CAS: 145040-37-5

Candesartan cilexetil bụ ọgwụ nwere ike, na-eme ogologo oge, yana nhọrọ angiotensin II ụdị 1 nnabata AT1 antagonist, candesartan.A na-agbanye ya ngwa ngwa na candesartan n'oge mmịnye eriri afọ.Mgbe hydrolysis nke candesartan cilexetil na candesartan n'oge absorption nke eriri afọ, candesartan na-ahọrọ angiotensin II maka njikọ nke angiotensin II receptor subtype 1 AT1 na akwara dị nro, na-egbochi angiotensin II-mediated vasoconstriction na ịkpata vasodilatation.Na mgbakwunye, antagonism nke AT1 na gland adrenal na-egbochi njikọ nke angiotensin II na-akpali aldosterone na nzuzo site na cortex adrenal;sodium na mwepu mmiri na-abawanye, na-esote mbelata olu plasma na ọbara mgbali.