dUMP, 2′-Deoxyuridine-5′-monophosphate, nnu disodium CAS:42155-08-8

2′-Deoxyuridine-5′-monophosphate (dUMP) bụ ihe sitere na nucleotide nke na-etinye aka na mmepụta na ndozi DNA. Ọ na-eje ozi dị ka ihe na-ebute ụzọ maka dTTP (deoxythymidine triphosphate), nke bụ ihe owuwu dị mkpa maka mmeghari DNA. dUMP bụkwa ihe dị mkpa na usoro nke biosynthesis thymidylate, ebe a na-agbanwe ya ka ọ bụrụ dTMP (deoxythymidine monophosphate) site na enzyme thymidylate synthase. Mgbanwe a dị mkpa maka ịnọgide na-enwe nguzozi nucleotide kwesịrị ekwesị na iguzosi ike n'ezi ihe DNA n'ime sel.

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Nkọwa Ngwaahịa

Akara Ngwaahịa

Ngwa na Mmetụta

Njikọ DNA: dUMP na-eje ozi dị ka ihe na-ebute ụzọ maka deoxythymidine triphosphate (dTTP), nke dị mkpa maka mmụba DNA. Mgbanwe nke dUMP ka ọ bụrụ dTMP bụ nzọụkwụ dị mkpa na njikọta nke nucleotides thymidine, nke dị oke mkpa maka mmụba ziri ezi nke ihe mkpụrụ ndụ ihe nketa n'oge nkewa sel.

Njiko Thymidylate: dUMP bụ ihe e ji eme enzyme thymidylate synthase, nke na-akwalite mgbanwe nke dUMP ka ọ bụrụ dTMP. Usoro a dị mkpa maka ịnọgide na-enwe nguzozi nucleotide kwesịrị ekwesị na mkpụrụ ndụ na ijide n'aka na DNA na-agbanwe agbanwe.

Ọgwụ Mgbochi Ọrịa Kansa: Thymidylate synthase, enzyme nke dị na ntụgharị nke dUMP gaa na dTMP, bụ ihe a na-elekwasị anya maka ụfọdụ ọgwụ mgbochi ọrịa kansa. Ịgbochi thymidylate synthase nwere ike imebi njikọ DNA na mmụba nke mkpụrụ ndụ, na-eme ka ọ bụrụ ihe a na-elekwasị anya maka chemotherapy.

Ngwaọrụ Nnyocha: A na-eji dUMP eme nnyocha gbasara bayoloji na molekul dị ka ihe ndabere iji mụọ usoro nke njikọta DNA, ndozi, na metabolism nucleotide. A na-ejikwa ya na nyocha enzymatic iji nyochaa ọrụ nke thymidylate synthase na enzymes ndị metụtara ya.

Nkwakọ ngwaahịa:

Ozi Mgbakwunye:

Ihe mejupụtara ya	C9H14N2NaO8P
Nnwale	99%
Ọdịdị	Ntụ ntụ ọcha
Nọmba CAS	42155-08-8
Nkwakọ ngwaahịa	Obere na nnukwu
Ndụ nchekwa	afọ 2
Nchekwa	Debe n'ebe dị jụụ ma kpọọ nkụ
Asambodo	ISO.