Sitagliptin Phosphate CAS:654671-78-0 Onye Na-eweta Ngwaahịa

Sitagliptin Phosphate bụ ọgwụ trizolopyrazine dipeptidyl peptidase IV na-egbochi ọrịa shuga. A na-akwado Sitagliptin n'oge na-adịbeghị anya maka ọgwụgwọ ọrịa shuga ụdị nke abụọ. Sitagliptin phosphate bụ ọgwụ ndị na-egbochi dipeptidyl peptidase Ⅳ (DDP-4) nke ụlọ ọrụ German Merck mepụtara ma nweta nkwenye US Food and Drug Administration maka ọgwụgwọ ọrịa shuga ụdị nke abụọ, ọ bụ ọgwụ ọhụrụ na-egbochi ọrịa shuga, nwere ike imeziwanye ikike ahụ iji belata ọkwa glucose dị elu n'ọbara, yana mmụba dị ukwuu nke incretin na-eme site na igbochi ọrụ nke enzyme a, gụnyere ọkwa nke glucagon-like peptide 1 na insulinotropic peptide nke na-adabere na glucose, si otú a na-akpali pancreas imeziwanye mmepụta insulin ma kwụsị mmepụta glucose na imeju, ma mechaa belata mmetụta ahụike nke mkpokọta glucose ọbara.